Larry began to experience symptoms in September of 2007, including fasciculations that became more and more severe, difficulty manipulating his fingers especially when it was cold, and trouble with fine motor skills for tasks such as buttoning his shirt, tying his shoes, or snapping his fingers.  After working as a steel fabricator and crane operator for 35 years, Larry attributed his symptoms to “arthritis.”  However, over the next 2  1/2 years it became gradually more difficult to lift heavy objects, to do intricate work with his fingers such as threading a needle, and it eventually became difficult to write.  By the middle of 2009,   Larry began to notice muscle atrophy in his hands and forearms.  In March 25, 2010, after several EMGs and MRIs, Larry was given the devastating diagnosis of ALS.