By THOMAS
M. BURTON
January 29, 2008
Researchers
studying brain injury believe they've found a common
thread running through many cases of seemingly unrelated
social problems: a long-forgotten blow to the head.
They've
found that providing therapy for an underlying brain
injury often helps people with a variety of ills ranging
from learning disabilities to chronic homelessness and
alcoholism. If broadly verified, the findings could have
a significant impact in dealing with such intractable
difficulties.
That severe
head injuries can lead to cognitive and behavioral
problems is widely accepted. The U.S. Centers for
Disease Control and Prevention estimates 5.3 million
Americans suffer from mental or physical disability that
is due to brain injury.
What's new
is the contention of some researchers that there are
many other cases where a severe past blow to the head,
resulting in unconsciousness or confusion, is the
unrecognized source of such problems. "Unidentified
traumatic brain injury is an unrecognized major source
of social and vocational failure," says Wayne A. Gordon,
director of the Brain Injury Research Center at Mount
Sinai School of Medicine in New York, where much of the
research is being done.
Research by
his team has consistently found high rates of "hidden"
head trauma when screening various populations in New
York schools, addiction programs and the general
population. The CDC acknowledges its 5.3 million
estimate is an undercount based on hospital admissions;
it doesn't include people who sought no treatment for a
severe blow to the head or who were sent home from a
doctor's office or emergency room with little treatment.
UNDERLYING CAUSE
• New Findings:
Researchers say a blow to the head years
earlier may be linked to problems later in
life, such as learning disabilities,
homelessness and alcoholism.
• Early
Identification: Some schools are trying
to identify children who may have had head
injuries to provide special help in
education.
• The Impact:
The findings are offering new hope to adults
coping with the onset of disorders such as
losing the ability to read or concentrate.
Causes of
brain injury can include bike and car accidents, sports
concussions such as those suffered by professional
football players, and abuse and falls that can date back
to childhood. Doctors say about 85% of common falls in
infancy don't produce long-term deficits, but that some
do.
To be sure,
it's difficult to connect with any certainty a long-ago
blow to the head to memory and cognition problems years
later. Other researchers point out that many people do
recover completely from severe head injury, and mental
problems arise from other causes. Moreover, Mount
Sinai's findings haven't all been published, nor have
they been widely evaluated at other institutions.
Lost
Ability to Read
Mount
Sinai's research involves people like Kate Gleason, a
business-college instructor who over the course of a
year lost her ability to read, keep her home orderly and
even maintain friendships.
In 1998,
Ms. Gleason tried to open a window in her New York
apartment building's hallway, but the heavy top window
fell and bashed her on the head. She was treated by
doctors at a local hospital, who she says let her walk
home and told her she'd be fine. But on the way back,
she was still so confused she had to hang onto lampposts
and buildings to keep from losing her way.
A slim,
auburn-haired woman then in her mid-40s, Ms. Gleason
kept teaching, but found that the bright lights and
hectic office were overwhelming. She says she confided
in a boss about her troubles and soon lost her job.
After that, she made ends meet by returning to
proofreading work, but she slowly withdrew socially.
She didn't
pay bills on time. Her house was a mess. "Years and
years went by, and I had lots of problems," she says. "I
didn't know it was from the head injury. I just thought
I had a clutter problem." By 1999, Ms. Gleason, who has
a master's from Columbia University, was "so bad on the
level of functioning as a college grad that I wanted to
die." She had no idea why.
Then about
two years ago, she got a strange letter from Mount
Sinai: It asked if she was having trouble thinking or
solving problems or if she became easily overwhelmed. It
turned out Mount Sinai doctors were reaching out to
people whose medical records showed a blow to the head.
Ms. Gleason responded, and when researchers interviewed
her, she began to sob, saying, "Life is just so hard."
On what was
to be the first day of an attention and memory program,
Ms. Gleason got lost in the maze of hospital hallways
and began crying again. Once she found the site, she
discovered she wasn't the only patient who got lost a
lot, or who cried.
For five
days a week for six months, she worked through five
hours of attention exercises, reading articles to
explain the main idea, interpreting charts and graphs,
taking classes on how to take apart a problem and reduce
it to smaller steps, writing mock "advice columns" on
how to handle life issues.
At first,
she found the work so intense she needed a break every
15 minutes. By a week later, she could concentrate a
little longer. She completed the program in August 2006,
eight years after the window struck her. Now she's
studying to be a church-based counselor. "That program
gave me my life back," she says.
A group for
whom the research on undiagnosed head injuries could be
especially relevant is the homeless. Assessments by
Mount Sinai researchers of about 100 homeless men in New
York found that 82% had suffered brain injury in
childhood, primarily as a result of parental abuse.
An
epidemiological study in 2000 was larger. Researchers
went door-to-door in New Haven, Conn., interviewing
5,000 people, 7.2% of whom recalled a past blow to the
head that was followed by unconsciousness or a period of
confusion. In follow-up testing, the researchers found
that those who reported such injuries had more than
twice the rate of depression and of alcohol and drug
abuse as others.
They also
had sharply elevated rates of panic disorder,
obsessive-compulsive disorder and suicide attempts, say
the researchers, led by Jonathan Silver of New York
University.
Such
research began in the late 1980s with Mount Sinai's Dr.
Gordon and Mary Hibbard, both Ph.D. psychologists
specializing in rehabilitation and neuropsychology. In
questioning patients referred to them, they were struck
by how often they turned up a history of a brain injury
that wasn't in the patients' medical records.
Using a
questionnaire they devised, they tried to determine how
many children in the city school system had head
injuries that were followed by cognitive difficulties.
At one school, 10% of students told of having once had a
significant head injury. Later testing of these children
frequently "was suggestive of impairments," Dr. Hibbard
says.
Next, with
a grant from the U.S. Department of Education, they set
out to determine how many pupils enrolled in programs
for children with learning disabilities had ever
suffered a hard blow to the head. The results were
startling: About 50% had.
"The
accident can be three months ago, but by the time the
symptoms happen, the accident is forgotten. Nobody puts
it together," says Tamar Martin, a psychologist in the
program. The team worked with about 400 children,
finding that many children who'd had brain injuries were
lost in regular learning-disabilities classrooms.
They have
trouble with their memory from day to day, and teachers
can assume they're not trying hard, Dr. Martin says.
They need more breaks between topics. But their
performance varies greatly from day to day, and a
teacher can also erroneously perceive this fluctuation
as lack of initiative.
Just giving
such children more time often helps, she says, as do
special prompts from teachers. For instance, Dr. Martin
says, a teacher may say, "In a couple of minutes, I am
going to ask you about problem No. 10," and give the
child time to prepare before officially asking.
High
Intellect
One
14-year-old girl had a high intellect, but after she was
hit by a car, she suddenly couldn't do outlines or
organize her time, her mother says in an interview. "Her
processing was slower," adds Michelle Kornbleuth,
another psychologist in the Mount Sinai program. "She
was frustrated, and her scores came out in the average
range."
With Dr.
Kornbleuth's help, the girl was allowed to take exams
privately in an office and could concentrate better.
With such accommodations, she completed high school and
went on to graduate from prestigious Smith College.
Kansas
systematically tries to identify brain injuries among
the "learning disabled." School social workers and
teachers with special training across the state show
other teachers how to recognize and work with the
brain-injured, says Janet Tyler, director of a
neurologic-disabilities project in the state education
department.
"When you
look at children with learning disabilities or behavior
problems, there's often an underlying high percentage of
children with traumatic brain injury. We're looking at
about 20%," she says.
In Mulvane,
Kan., Sandy Baca's son Timothy, who was hit by a car at
age 2, struggled in school for years. Ms. Baca says that
once teachers understood the difference between brain
injury and other disability, "they found ways for him to
be successful. If he couldn't do the work one day, they
would lower expectations for the day." Ultimately, he
finished high school.
The Mount
Sinai team evaluates people via a battery of "neuropsych"
tests lasting up to nine hours. They are shown pictures
of objects, then asked minutes later what they saw. They
see a complex geometric design with triangles, lines and
circles and are asked to draw it from memory. They're
shown a series of multiple random letters and asked to
cross out, say, the "c" and "e" every time they see one.
On a recent
morning, a 44-year-old manager at a New York investment
firm was working on attention training with a
postdoctoral fellow. He had sustained several sports
concussions as a younger man and then in recent years
twice banged his head hard. Lately, he had been feeling
confused. Commuting between New York City and Long
Island, he boarded the wrong train three days in a row.
In the
first of several exercises, the patient was asked to
read a page of text while crossing out all words ending
in "ing," and then to answer questions about what he'd
read. The first time through, he caught only seven of 12
"ing" words. A second test asked him to choose a word
that didn't belong in a group of five, while listening
to other words and pressing a buzzer when he heard words
with four letters.
About five
years ago, the Mount Sinai team began looking at
residents of New York centers for alcoholism and drug
abuse. They evaluated 845 patients and determined that
54% had once suffered a hard blow to the head. Of
course, some had injuries after they began drinking, so
there is a certain chicken-and-egg problem with that
number.
Link to
Addiction
Steven
Kipnis, medical director of a New York state agency for
alcoholism and addiction, says his work with counselors
convinces him that many of the patients became alcoholic
or addicted in part because of a head injury, and
knowing about it helps in treatment.
"Someone
can get hit in the head with a softball and still be
working. They tend to be in denial. They get mood
swings, they yell at a spouse. It's a slow downward
spiral, and that's when alcohol and drugs" become an
option, he says.
The agency
has a program specifically for the brain-injured at the
R.E. Blaisdell Addiction Treatment Center in Orangeburg,
N.Y. A counselor there, Steve Oswald, tells of one
patient who dropped out of a general alcoholism program
three times before the program for the brain-injured
began, and then successfully completed the program.
In 2006,
Mount Sinai's Dr. Gordon began to work with Common
Ground, a New York nonprofit that builds housing for the
homeless. About 70% of 100 homeless people they tested
came out in the 10th percentile or lower for memory,
language or attention, says the group's director of
psychiatric services, Jennifer Highley. Questioning
uncovered that 82% had a significant blow to the head
prior to becoming homeless, usually from severe parental
abuse during childhood.
"People get
abused as kids, making them inattentive in school and
sometimes unable to learn," says Ms. Highley. She says
head injury and the emotional fallout from abuse can
lead to alcoholism and addiction, and "that combination
creates the inability to function and often leads to
homelessness."
|